人类Pin1在食管癌组织中的表达的任务书任务：撰写关于人类Pin1在食管癌组织中的表达的论文要求：1.描述Pin1基因和蛋白质的结构及功能；2.综述Pin1在癌症中的作用和机制；3.分析已有的文献，阐述Pin1在食管癌组织中的表达情况及其与食管癌发生、发展的关系；4.讨论Pin1在食管癌的诊断、治疗及预后方面的应用前景。参考文献：1.Lu,K.P.,&Zhou,X.Z.(2007).TheprolylisomerasePIN1:apivotalnewtwistinphosphorylationsignallinganddisease.NaturereviewsMolecularcellbiology,8(11),904-916.2.Rustighi,A.,Zannini,A.,Tiberi,L.,Sommaggio,R.,Piazza,S.,Sorrentino,G.,...&DelSal,G.(2014).Prolyl-isomerasePin1controlsnormalandcancerstemcellsofthebreast.EMBOmolecularmedicine,6(7),990-1007.3.Han,X.,Shen,M.,Gao,P.,Wang,X.,Zheng,J.,Wang,J.,&Lu,X.(2017).ExpressionandclinicalsignificanceofPin1inhumangastriccancer.Medicaloncology,34(2),23.4.Peng,C.,Chen,Y.,Yang,Z.,Zhang,H.,Osterby,L.,Rosmarin,A.G.,&Li,Y.P.(2011).PTENisatumorsuppressorinCMLstemcellsandBCR-ABL-inducedleukemiasinmice.Blood,118(26),6900-6911.5.Stewart,G.S.,&Lu,K.P.(2013).TheessentialfunctionsofnuclearPTENinpromotingDNAdamagerepairandcelldeathinresponsetogenomicstress.Naturecellbiology,15(7),617-625.