UPLC-MS/MS测定14种农产品中噻虫嗪和噻虫胺残留的研究的开题报告【摘要】本项目旨在开展一项分析14种农产品中噻虫嗪和噻虫胺残留的UPLC-MS/MS测定研究。噻虫嗪和噻虫胺是一种广泛使用的杀虫剂，但长期以来，其残留量对人体健康和环境安全造成的潜在风险引起了广泛关注。因此，建立一种高效、准确、灵敏的定量分析方法用于噻虫嗪和噻虫胺残留的检测是非常必要的。在该项目中，将收集包括蔬菜、水果、谷物和茶叶等14种常见农产品样品，样品的前处理采用超声波提取技术，获得清洁的提取液进行UPLC分析。在分析过程中，将选用ABI4000QTRAP三重四极杆质谱仪结合UPLC进行定性和定量分析。同时，通过内标法校正加标回收率。建立标准曲线、检验方法的可靠性和灵敏度。最后，在优化实验参数后，确立最优的分析方法。在此基础上，将分别进行14种农产品中噻虫嗪和噻虫胺残留的测定和分析，确认其是否超过国家相关标准。【关键词】噻虫嗪，噻虫胺，残留，超声波提取，UPLC-MS/MS【Abstract】ThisprojectaimstoconductaUPLC-MS/MSdeterminationofthiaclopridandacetamipridresiduesin14typesofagriculturalproducts.Thiaclopridandacetamipridarewidelyusedinsecticides,buttheirpotentialriskstohumanhealthandenvironmentalsafetycausedbyresidualamountshaveattractedwidespreadattentionforalongtime.Therefore,itisverynecessarytoestablishanefficient,accurate,andsensitivequantitativeanalysismethodforthedetectionofthiaclopridandacetamipridresidues.Inthisproject,14commonagriculturalproductsamplesincludingvegetables,fruits,grains,andteawillbecollected.Thesamplepretreatmentwilladoptultrasonicextractiontechnology,andthecleanextractwillbeobtainedforUPLCanalysis.Intheanalysisprocess,ABI4000QTRAPtriplequadrupolemassspectrometercombinedwithUPLCwillbeselectedforqualitativeandquantitativeanalysis.Atthesametime,theinternalstandardmethodwillbeusedtocalibratetherecoveryrateofthestandardsample.Establishstandardcurve,testthereliabilityandsensitivityofthemethod.Finally,afteroptimizingtheexperimentalparameters,theoptimalanalysismethodwillbeestablished.Basedonthis,thedeterminationandanalysisofthiaclopridandacetamipridresiduesin14typesofagriculturalproductswillbecarriedoutrespectivelytoconfirmwhethertheyexceedthenationalrelevantstandards.【KeyWords】thiacloprid,acetamiprid,residue,ultrasonicextraction,UPLC-MS/MS