系统医学2024年2月第9卷第3期·临床医学系统研究·DOI：10.19368/j.cnki.2096-1782.2024.03.091D-二聚体监测在急性下肢深静脉血栓形成患者置管溶栓中疗效判断的意义刘瑶如东县中医院介入放射科，江苏南通226400[摘要]目的分析在急性下肢深静脉血栓形成患者置管溶栓中采取D-二聚体监测对疗效判断的意义。方法选取2021年1月—2022年12月在如东县中医院治疗的60例急性下肢深静脉血栓形成患者为研究对象，按照随机数表法分为对照组和观察组，每组30例。对照组实施足背静脉溶栓治疗，观察组实施置管溶栓治疗。对比两组D-二聚体指标、临床疗效。结果治疗后1~7d，观察组D-二聚体指标水平依次为（68.14±2.13）、（70.71±2.29）、（75.76±2.01）、（71.58±2.37）、（61.24±2.22）、（52.21±2.56）、（28.22±2.01）mg/L，均比对照组更高，差异有统计学意义（t=66.211、48.766、49.042、49.693、58.197、40.223、13.706，P均<0.05）。治疗后第8天，两组D-二聚体指标水平对比，差异无统计学意义（P>0.05）。观察组治疗后静脉通畅评分（[4.63±1.42）分]比对照组更低，静脉通畅率（[62.98±14.26）%]比对照组更高，差异有统计学意义（P均<0.05）。结论采用D-二聚体监测方式，能够较为准确评估急性下肢深静脉血栓患者置管溶栓的疗效。[关键词]D-二聚体；急性下肢深静脉血栓形成；置管溶栓；疗效判断[中图分类号]R543文献[标识码]A文章编号[]2096-1782（2024）02(a)-0091-04SignificanceofD-dimerMonitoringinEvaluatingtheTherapeuticEffectofCatheterizationThrombolysisinPatientswithAcuteDeepVenousThrombosisofLowerExtremitiesLIUYaoDepartmentofInterventionalRadiology,RudongCountyHospitalofTraditionalChineseMedicine,Nantong,JiangsuProvince,226400China[Abstract]ObjectiveToanalyzethesignificanceofD-dimermonitoringintheevaluationoftherapeuticeffectofcatheterizationthrombolysisinpatientswithacutelowerextremitydeepvenousthrombosis.MethodsFromJanuary2021toDecember2022,60patientswithacutelowerextremitydeepvenousthrombosistreatedinRudongCountyHospitalofTraditionalChineseMedicinewereselectedastheresearchobjects.Accordingtotherandomnumbertablemethod,theyweredividedintocontrolgroupandobservationgroup,with30casesineachgroup.Thecontrolgroupwastreatedwithdorsalveinthrombolysis,andtheobservationgroupwastreatedwithcatheterizationthrombolysis.TheD-dimerindexandclinicalefficacywerecomparedbetweenResultstwogroups.From1to7daysaftertreatment,TheD-dimerindexesintheobservationgroupwere(68.14±2.13),(70.71±2.29),(75.76±2.01),(71.58±2.37),(61.24±2.22),(52.21±2.56),(28.22±2.01)mg/L,whichwereallhigherthanthoseofthecontrolgroup,andthedifferenceswerestatis⁃ticallysignificantt=66.211,(48.766,49.042,49.693,58.197,40.223