HIV感染者骨密度降低的发生率及其危险因素分析的开题报告摘要：HIV感染者在接受抗逆转录病毒治疗时，常出现骨质疏松和骨折等问题，严重影响患者的生活质量。本研究旨在探讨HIV感染者骨密度降低的发生率及其危险因素，为该人群提供有效的预防和治疗措施。文献综述表明，HIV感染可以影响骨代谢、促进炎性因子释放、导致内分泌紊乱等，使得骨密度下降的风险增加。可能的危险因素包括接受抗逆转录病毒治疗时间、慢性肝炎、糖尿病、过度饮酒等。目前研究结果并不一致，需要进一步的人群研究来确定与HIV骨密度降低相关的危险因素。本研究计划通过问卷调查和生物学检测等方法，进行人群研究，并使用统计学方法来分析数据，以确定影响HIV感染者骨密度降低的危险因素，为其提供更好的预防和治疗策略。关键词：HIV感染者、骨密度、危险因素、抗逆转录病毒治疗Abstract:HIV-infectedpatientsoftensufferfromosteoporosisandfractures,whichseriouslyaffecttheirqualityoflife.ThisstudyaimstoinvestigatetheincidenceandriskfactorsofdecreasedbonedensityinHIV-infectedpatients,andtoprovideeffectivepreventionandtreatmentmeasuresforthispopulation.LiteraturereviewshowsthatHIVinfectioncanaffectbonemetabolism,promotethereleaseofinflammatoryfactors,andcauseendocrinedisorders,thusincreasingtheriskofdecreasedbonedensity.Possibleriskfactorsincludethedurationofantiretroviraltherapy,chronichepatitis,diabetes,andexcessivealcoholconsumption.However,currentresearchresultsareinconsistent,andfurtherpopulationstudiesareneededtodeterminetheriskfactorsassociatedwithHIV-associatedbonedensityloss.Thisstudyplanstoconductapopulationstudythroughquestionnairesurveyandbiologicaldetectionmethods,andusestatisticalmethodstoanalyzedatatodeterminetheriskfactorsthataffectthedecreaseofbonedensityinHIV-infectedpatients,andprovidebetterpreventionandtreatmentstrategies.Keywords:HIV-infectedpatients,bonedensity,riskfactors,antiretroviraltherapy