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一、转化区(移行带)一、转化区(移行带)一、转化区(移行带)二、鳞状上皮化生二、鳞状上皮化生三、宫颈病变的概念CompanyLogo不同诊断术语的含义四、宫颈病变三阶梯检查五、阴道镜检查指征(6)不典型腺上皮细胞(AGC);(7)腺原位癌(AIS);(8)腺癌;(9)巴氏分级标准中≥巴氏Ⅱb级以上的结果;(10)高危型HPV检测结果阳性(需注明hpv检测方法,如:hc-2法、hpv基因分型法特别是16、18型阳性、PCR法)2、裸眼醋酸染色或复方碘染色后肉眼观察(via/vili)结果异常。3、裸眼直观为宫颈溃疡、肿块或可疑宫颈浸润癌。4、可疑病变处指导性活检5、宫颈锥切前确定病变范围6、宫颈尖锐湿疣7、慢性宫颈炎长期治疗无效8、阴道和外阴病变:阴道和外阴上皮内瘤样变、早期阴道癌、阴道腺病、梅毒、结核、尖锐湿疣等questionImportanceMethodsRandomizationInterventionsInterventionGroupControlGroupSafetyGroupproceduresThemaintrialobjectivewastocomparetheratesofcervicalintraepithelialneoplasia(CIN)grade3orgreater(CIN3+)48monthsafterbaselinescreeningwithprimaryHPVvsLBC.Detailedtrialmethodsandresultshavebeenpreviouslydescribed.AsoutlinedinFigure1,round1referstothebaselinescreenandany12-monthfollow-upresultsinboththeinterventionandcontrolgroups.The24-monthscreenroundrefersonlytowomeninthecontrolgroupbecausetheinterventiongroupdidnotreceive24-monthscreening,andthis24-monthscreenroundincluded24-monthscreenresultsand36-monthfollow-upresults.The48-monthexitroundrefersto48-monthexitscreeningresults(plus24-monthresultsforthecontrolgroup)andassociatedoutcomesforboththeinterventionandcontrolgroupsTrialOutcomesResultsDiscussionConclusionsTHANKYOU!