ThePredictiveValueofChangesinEffectiveConnectivityforHumanLearningC.Büchel,etal.Science283,1538(1999);DOI:10.1126/science.283.5407.1538Thiscopyisforyourpersonal,non-commercialuseonly.Ifyouwishtodistributethisarticletoothers,youcanorderhigh-qualitycopiesforyourcolleagues,clients,orcustomersbyclickinghere.Permissiontorepublishorrepurposearticlesorportionsofarticlescanbeobtainedbyfollowingtheguidelineshere.Thefollowingresourcesrelatedtothisarticleareavailableonlineatwww.sciencemag.org(thisinformationiscurrentasofMarch24,2010):Updatedinformationandservices,includinghigh-resolutionfigures,canbefoundintheonlineversionofthisarticleat:http://www.sciencemag.org/cgi/content/full/283/5407/1538Thisarticlehasbeencitedby189article(s)ontheISIWebofScience.Thisarticlehasbeencitedby36articleshostedbyHighWirePress;see:http://www.sciencemag.org/cgi/content/full/283/5407/1538#otherarticlesThisarticleappearsinthefollowingsubjectcollections:onMarch24,2010Neurosciencehttp://www.sciencemag.org/cgi/collection/neurosciencewww.sciencemag.orgDownloadedfromScience(printISSN0036-8075;onlineISSN1095-9203)ispublishedweekly,exceptthelastweekinDecember,bytheAmericanAssociationfortheAdvancementofScience,1200NewYorkAvenueNW,Washington,DC20005.Copyright1999bytheAmericanAssociationfortheAdvancementofScience;allrightsreserved.ThetitleScienceisaregisteredtrademarkofAAAS.REPORTSpeptonebrothsupplementedwith0.1%glucoseatpreparationofTGase2,B.TaylorforassistancewithandCraniofacialResearch(P.S.)andAI32556from25°Cwithshakingat100rpm.theanimalexperiments,andC.M.Allenforhistolog-theNationalInstituteforAllergyandInfectiousDis-30.Animalstudieswereconductedinaccordancewithicalassessmentsofinfectedmousetissues.Supporteases(P.L.F.).theNIHguidelinesforthecareanduseoflaboratoryforthisresearchwasprovidedfromgrant1R01animals.WethankA.JacksonforassistancewithDE11375-05A2fromtheNationalInstituteofDental30October1998;accepted3February1999theensuingasymptoticlearningcurves(Fig.