Selenium interactions and toxicity.pdf
上传人:yy****24 上传时间:2024-09-10 格式:PDF 页数:16 大小:259KB 金币:16 举报 版权申诉
预览加载中,请您耐心等待几秒...

Selenium interactions and toxicity.pdf

Seleniuminteractionsandtoxicity.pdf

预览

免费试读已结束,剩余 6 页请下载文档后查看

16 金币

下载此文档

如果您无法下载资料,请参考说明:

1、部分资料下载需要金币,请确保您的账户上有足够的金币

2、已购买过的文档,再次下载不重复扣费

3、资料包下载后请先用软件解压,在使用对应软件打开

CellBiolToxicol(2012)28:31–46DOI10.1007/s10565-011-9203-9Seleniuminteractionsandtoxicity:areviewSeleniuminteractionsandtoxicityIwonaZwolak&HalinaZaporowskaReceived:4May2011/Accepted:2September2011/Publishedonline:14September2011#SpringerScience+BusinessMediaB.V.2011AbstractSeleniumisanessentialtraceelementforagainstoxidativestressinducedbycadmiuminmammals.Throughselenoproteins,thismineralpar-variousanimaltissuesproducedpromisingresults.ticipatesinvariousbiologicalprocessessuchasReportssuggestthatseleniumprotectionagainstantioxidantdefence,thyroidhormoneproduction,toxicityofarsenicandcadmiumismediatedviaandimmuneresponses.Somereportsindicatethatasequestrationoftheseelementsintobiologicallyinerthumanorganismdeficientinseleniummaybeproneconjugates.Selenium-dependentantioxidantenzymestocertaindiseases.Adversehealtheffectsfollowingprobablyplayasecondaryroleinarsenicandseleniumoverexposure,althoughveryrare,havebeencadmiumdetoxification.Sofar,fewstudieshavefoundinanimalsandpeople.Contrarytoselenium,evaluatedseleniumeffectsonchromium(III)andvana-arsenicandcadmiumareregardedastoxicelements.diumactionsinmammals.Still,theyshowthatseleniumBothareenvironmentalandindustrialpollutants,andmayinteractwiththeseminerals.Takentogether,theexposuretoexcessiveamountsofarsenicorcadmiumrecentfindingsregardingseleniuminteractionwithcanposeathreattomanypeople’shealth,especiallyotherelementsextendourunderstandingofseleniumthoselivinginpollutedregions.Twootherelements,biologicalfunctionsandhighlightseleniumasavanadiumandchromium(III)intraceamountsarepotentialcountermeasureagainsttoxicityinducedbybelievedtoplayessentialphysiologicalfunctionsinarsenicandcadmium.mammals.ThisreviewsummarizesrecentstudiesonseleniuminteractionswitharsenicandcadmiumandKeywordsArsenic.Cadmium.Seleniumseleniuminteractionswithvanadiumandchromiuminteractions.Toxicity.Traceelementsinmammals.HumanstudieshavedemonstratedthatseleniummayreducearsenicaccumulationintheAbbreviationsorganismandpro