摘要设备维修管理体系经历了事后维修、预防维修和生产维修三个阶段，单一的事后维修和计划维修已经制约了企业的发展。为了提高设备管理水平、降低维修费用，基于全员参与的TPM现代设备管理模式正逐步被企业所接受。随着API生产企业生产过程自动化、设备连续化和复杂化的发展，关键设备已成为决定API企业生产经营的重要因素。本文通过收集相关资料、现场调研、风险评估等方式进行论据的充实，用理论加实践的方法对TPM设备管理模式在关键设备中的推行进行深入分析，得出推行的方式。旨在总结在API生产企业中推行对关键设备实施全员参与的TPM设备管理的方法，降低维修费用，从而帮助促进企业生产经营活动的顺畅进行。本文以API企业的关键设备玛斐离心机为例，进行了案例的分析和总结。通过对其推行TPM管理前后的设备故障停机时间、维修费用为对比，透彻地显示推行TPM管理的效果。本篇论文的研究结论即在API企业关键设备中推行可以有效降低关键设备故障发生率、降低维修成本、保障企业持续生产经营、创造更多的经济效益，企业推行关键设备的TPM设备管理模式是保持企业健康持续运行的有效手段，也是适应时代发展的理性选择。关键词：API企业关键设备TPM管理维修费用ImplementingTPMtoKeyAPIManufacturingEquipmentstoReduceMaintenanceCostsAbstractTheequipmentmaintenancemanagementsystemhasthreestages,whichareafterwardsmaintenance,preventivemaintenanceandproductionmaintenance.Thesinglemodelofafterwardsmaintenanceorplannedmaintenancehasrestrictedthedevelopmentofenterprises.Inordertoimproveequipmentmanagementandreduceequipmentmaintenancecosts,theTPMmanagementmodeofmodernequipment,basedonfullparticipationofenterprises,isgraduallybeingaccepted.Withthedevelopmentofautomation,equipmentcontinuumandthecomplexityofAPIproductionprocess,thekeyequipmentshavealreadybecomethedecisivefactorsintheproductionandmanagementofAPImanufacturers.Thispaperenrichestheargumentsbywaysofcollectingrelevantdata,fieldresearch,riskassessmentetc,usesboththeoreticalandparticlemethodstoanalysistheimplementationofTPMsysteminkeyequipment,andfindthewaysofimplementation.ItisaimedtosummarizetheAimstosummarizetheimplementationmethodinAPIenterprises’TPMdevicemanagementofkeyequipment,andreducemaintenancecosts,therebyhelpingenterpriseproductionandbusinessactivitiesrunningsmoothly.Inthispaper,theauthortookMaffeicentrifuge,apieceofkeyequipmentinAPImanufacturing,asanexampletoconductacaseanalysisandsummary.BycomparingtheequipmentfailurerateandmaintenancecostsbeforeandaftertheimplementationofTPMmanagement,itistothoroughlydemonstratetheeffectofTPMmanagement.TheConclusionsofthispaperisthattargetingthekeyequipmentsforAPIenterprisestoimplementtheTPMdevicemanag