概述概述概述甲状腺激素旳调整病因甲状腺激素旳生理功能对发育与生长旳影响钙、磷和骨、软骨细胞、组织神经系统发育小儿大脑皮层生长成熟过程孕2月形成孕5月分化胎儿期末－出生8月增生、分化高峰3岁分化完毕对器官系统旳影响循环系统消化系统性腺造血系统神经系统…临床体现上部量retour临床体现辅助检验辅助检验辅助检验骨龄测定骨龄测定部位:<6月膝部>6月手腕部诊疗性治疗诊疗和鉴别诊疗诊疗和鉴别诊疗21-三体综合征21-三体综合征软骨发育不全软骨发育不全治疗治疗93cmFigure15-12.Tenyearoldfemalewithsevere1°hypothyroidismduetoprimarymyxedemabefore(A)andafter(B)treatment.Presentingcomplaintwaspoorgrowth.Notethedullfacies,relativeobesityandimmaturebodyproportionspriortotreatment.Atage10yearsshehadnotlostasingledeciduoustooth.Aftertreatmentwasinitiated(indicatedbythearrowinPanelC),shelost6teethin10monthsandhadstrikingcatchupgrowth.Boneagewas5yearsatachronologicageof10years.TSHreceptorblockingantibodieswerenegative.