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BloodTransfusionPromotesCancerProgression:ACriticalRoleforAgedErythrocytesBackgroundBackgroundBackgroundBackgroundBackgroundobjectiveMethodF344ratswereanesthetizedwithhalothane(vaporizer,2.5%)anda24GAi.v.cannulawasinsertedintothetailvein.Astandard3mlvolumecontainingdifferentquantitiesandfractionsofsaline-dilutedbloodconstituentswasslowlytransfusedduringa10minperiodTumorcellswereinoculatedattheendofthis10minperiodthroughthei.v.cannulaAssessmentImmediateandshort-lastingeffectofbloodtransfusionEffectofstorageintervalandhistocompatibilityEffectsofcellularandsolublefractionsRBCbutnotleukocytesmediatetheimpactofbloodtransfusiononMADB106lungtumorretentionTheeffectsofRBCtransfusioninthecontextofsurgeryandbloodlossEffectonsurvivalintheCRNK-16tumormodelConclusionsConclusionsMechanismMechanismMechanismQuestionableSolutiontotransfusion
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