保胎灵治疗早期先兆流产临床观察许晓芬1徐倩倩2(1，2.江苏省镇江市妇幼保健院，212001)[摘要]目的评价保胎灵治疗肾虚型早期先兆流产的临床疗效。方法将144例肾虚型先兆流产患者随机分为2组,治疗组68例口服保胎灵,对照组76例给予黄体酮、绒毛膜促性腺激素。比较2组治疗后的疗效及女性激素的影响。结果治疗组有效率87%;对照组有效率85%。2组总有效率比较均无显著性差异(P>0.05)。治疗组、对照组均能明显提高P、β-hCG水平(P均<0.05)。结论保胎灵能有效治疗肾虚型早期先兆流产,其疗效与黄体酮、绒毛膜促性腺激素治疗相当。保胎灵通过提高先兆流产患者血清P、β-hCG水平,改善女性激素失衡的状态，达到治疗先兆流产的目的。[关键词]早期先兆流产；肾虚型；保胎灵；黄体酮；绒毛膜促性腺激素ClinicalObservationonEarlyThreatenedAbortionwithBaotailingtabletsXuXiaofen1,XuQianqian2（XuXiaofen1,XuQianqian2,MaternalandHealthofZhenjiangcity,Zhenjiang212001,Jiangsu,China）[Abstract]ObjectiveToobservetheclinicalcurativeeffectofBaotailingtabletsonearlythreatenedabrortionpatientswithkidneydeficiency.Methods144threatenedabortionpatientswithkidneydeficiencywererandomlydividedintotwogroups.68caseswereintreatmentgroupandtreatedwithBaotailingtabletstakenorallyandtheother76caseswereincontrolgroupandtreatedwithProgesteroneandhumanchorionicgonadotropin(hCG).Thecomprehensivecurativeeffectaftertreatmentandtheinfluenceonendocrinehormoneinthegroupswerecompared.ResultIntreatmentgroup,thetotaleffectiveratewas87%.Incontrolgroup,thetotaleffectiveratewas85%.Therewerebothnosignificantdifferenceonthetotaleffectiveratebetweenthetwogroups(P>0.05).ThelevelsofPandβ-hCGinthetwogroupswereallobviouslyheightened(allP<0.05).ConlusionBaotailingtabletseffectivefortreatingearlythreatenedabortionpatientswithkideydeficiencyandthecomprehensivecurativeeffectiscorrespondwithProgestertoneandhCGBaotailingtabletscantreatearlythreatenedabortionpatientsthroughheighteningserumPandβ-hCGandimproveingthepositionofunbalanceendocrine.[Keywords]earlythreatenedabrortion;kidneydeficiency;Baotailingtablets;Progestertone;humanchorionicgonadotropin(hCG).先兆流产是指妊娠28周前，出现少量阴道流血或（和）下腹痛，宫颈口未开，胎膜未破，妊娠产物尚未排出，妊娠尚有希望继续者。妊娠12周内出现上述症状体征时，称早期先兆流产。先兆流产是妇产科常见病、多发病。先兆流产属中医学“胎漏”、“胎动不安”、“妊娠腹痛”的范畴。认为先兆流产的证型可分为肾虚、气血虚弱、血热和血瘀四个证型[1],研究发现先兆流产中以肾虚为主[2]，肾虚冲任不固则不能摄血养胎,发生胎漏、胎动不安,其病因多端,但与肾气不足关系尤为密切。本研究以黄体酮、绒毛膜促性腺激素（hCG）治疗为阳性对照组,研究保胎灵治疗早期先兆流产(中医辨证属肾虚型)的疗效，以及对激素孕酮（P）、β-hCG的影响。1临床资料1.