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SeriousintrapartumcomplicationAcomplexdisordercausedbyamnioticfluidenteringmaternalcircurationandclassicallycharacterizedbytheabruptonsetofhypotension,hypoxia,andconsumptivecoagulopathyIncidence:1:20000Mortality:80%intermpregnancyRuptureofmembraneHypertoniaofamnioncavityOpenbloodsinusInjuryofcervicalcanaloruterinewallPlacentaprevia,placentaabruption,placentamarginalsinusruptureAdherencesiteofplacentaPrematureruptureofmembrane,artificialruptureorstrippingofmembrane,artificialexpansionofcervixToostronguterinecontractionRigiditycontractionandprecipitatelabourcausedbyinappropriateusingofoxytocinandoperationincavityInjuryCervicallaceration,ruptureofuterus,uterineincisionincaesareansection,forcepcurettageInternalcervicalveinAmnioticfluidvolumeenteringmaternalcirculationrelatedto:strengthofcontractiondegreeofinjuryUterineplacentabed：BrokenvenuleinadherencesiteofplacentaFissureinadherencesiteofplacentaOpendeciduabloodsinusplacentamarginalvesselAmnioticpermeationpressureofamnioticcavity↑intensityofamnioticmembrane↓PathyphysiologyAmnioticfluid(Epithelialcell,mucus,meconium,vernixcaseosa,lanugo)Premonitorysymptom：Short-perioddysphoria,chillandshiver,coughanddyspnea,cyanosis,vomitatthetimeofruptureofmembraneSymptomsdisappearaftertreatmentinmildAFE,severeAFEarisethreestages:Respiratoryandcirculatoryfailure,shorkBleedingcausedbyDICAcuterenalfailureAcuterespiratoryandcirculatoryfailureObviouscyanosisDyspneaCoughingfrothysputum,raisedheartrate,moistralesinlungFallofbloodpressureComa,seizureSeverecases:scream,respiratoryarrest,cardiopulmonaryarrest，dieCoagulationdisordershypercoagulablestate→hypocoagulablestageBleedingofskin,mucosa,needleeye,incisionHematuria,hematemesisMassvaginalbleedingTypicalsymptomofDICMultipleorganfailure(MOF)AcuterenalfailureOliguriaurinevolume<400ml/24hor17ml/hAnuria<100ml/24h，metabolicdisturbanceAzotemiaObviousjaundice,asciteBloodsmeartofindamnioticvisibleparticleBedsidechestX-layBedsideECGorCDFIRight
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