脂肪组织源性干细胞分化为神经细胞及其治疗脑缺血的研究现状（完整版）实用资料(可以直接使用，可编辑完整版实用资料，欢迎下载）中国组织工程研究第16卷第1期2021–01–01出版ChineseJournalofTissueEngineeringResearchJanuary1,2021Vol.16,No.1ISSN1673-8225CN21-1581/RCODEN:ZLKHAH1531SouthernMedicalUniversity,Guangzhou510515,GuangdongProvince,China;2DepartmentofHistologyandEmbryology,BasicMedicalSchool,SouthernMedicalUniversity,Guangzhou510515,GuangdongProvince,ChinaZhuYan-fei,SouthernMedicalUniversity,Guangzhou501515,GuangdongProvince,ChinaCorrespondenceto:DongWei-ren,Doctor,Professor,Doctoralsupervisor,DepartmentofHistologyandEmbryology,BasicMedicalSchool,SouthernMedicalUniversity,GuangzhouSupportedby:theFoundationofTalentYoungTeachersofGuangdongUniversities,No.C1010086*;theTackleKeyProgramofFoshanCity,No.202108063*;MedicalDisciplinaryProjectofFoshanHealthBureau,No.2021177*Received:2021-04-06Accepted:2021-09-09脂肪组织源性干细胞分化为神经细胞及其治疗脑缺血的研究现状***朱衍菲1，王琳琳1，董为人2Differentiationofadipose-derivedstemcellsintonervecellsandtheirtransplantationforcerebralischemiaZhuYan-fei1,WangLin-lin1,DongWei-ren2AbstractBACKGROUND:Adipose-derivedstemcells(ADSCsfromthemesodermhavethepotentialofmultipledifferentiations.Itcandifferentiatetoneuronsunderspecificenvironmentsandthentransplantintoanimalmodelsofcerebralischemiawhichcanenhancetherecoveryofneurologicalfunction.OBJECTIVE:TomakeareviewofADSCsinthetreatmentofcerebralischemia,andtoanalyzecurrentproblemsandtoprospectthefuture.METHODS:PubMed,CNKI,CAJwereretrievedbycomputerwithkeywordsof“adipose-derivedstemcells,adipose-tissuederivedstemcells,adiposestemcells,differentiation,cerebralischemia”.ThelanguagewaslimitedforEnglishandChinese.Theliteraturesincludedclinicalresearch,basicresearch,andreviews.Repetitiveresearcheswereexcluded,and34documentsofthemwereinvolvedforfurtheranalysis.RESULTSANDCONCLUSION:Inrecentyears,manyresearchesshowthatADSCscanpromotetheneurologicalfunctionaftercerebralischemiaindifferentdegree.ButbynowthereisnoreportthatADSCscanbeinducedtomatureneurons.Howtodifferentiatetoneuronsaccur