核磁共振波谱.ppt
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WhylearnNMR?1.1ARemarkableField1.2Oneofthetwoleadingtechnologiesinstructuralbiology1.2OneofthetwoleadingtechnologiesinstructuralbiologyMolecularweightdistributionoftheNMRstructuresdepositedintheBrookhavenPDBasofDecember1997.1.3Greatcontributionstobiology1.4Milestones1.4MilestonesNMRApplications——A-ZNMRApplications——A-ZNMRApplications——A-ZBigScienceNMRAboutthiscourse——Whatwillbecovered?andwhatnot?相关课程Whatisrequired?课程要求课程设置Seminar专题Seminar专题要求参考书目Someliteraturerecommendations-J.N.S.Evans"BiomolecularNMRSpectroscopy",OxfordUniversityPress1995,ISBN0-198-54766-8(QP519.9.N83E941995).(stressonbiomolecularNMR,incl.proteins&nucleicacids,butalsoincludingacompact,yetconciseintroduction,nicebook,reasonablypriced)-H.Kessler,M.Gehrke,C.Griesinger,Angew.Chem.Int.Edn.Engl.1988,27,490-536.(goodreviewonall2Dtechniques,incl.productoperatorexplanation,stilluptodate)-W.R.Croasmun,W.M.K.Carlson,ed."Two-DimensionalNMRSpectroscopy;ApplicationsforChemistsandBiochemists",VCH1994,ISBN1-56081-664-3(QD/96/N8/T87/1987).(mixtureofintroductoryandapplicationchapters,onheteronuclearspectroscopyetc.,expensive)-D.Shaw,"FourierTransformNMRSpectroscopy",ElsevierScientificPublishingCo.,NewYork,1976(Res.QC/762/S45/2/1984).(goodonprincipleandfeaturesofFT,otherwiseoutdated)-J.K.M.Sanders,B.K.Hunter,"ModernNMRSpectroscopy,AGuideforChemists",OxfordUniversityPress,2nded.1993(QD/96/N8/S25).(noproductoperatordescription,butverygooddescriptionofapplicationsfor2Dtechniques,incl.examplespectra).-J.Cavanagh,W.J.Fairbrother,A.G>PalmerIII,N.J.Skelton,"ProteinNMRSpectroscopy,PrinciplesandPractice",AcademicPress,SanDiego1996,ISBN0-12-164490-1(QP551.P697261995)(Lotsoftheory,quantum-mechanics&productoperators,FT,relaxationmeasurements,despitetitlelargesectionon2Dmethods)JournalsMagneticResonanceJournals